{"_buckets": {"deposit": "b59c17ae-211f-47d6-a64d-33a0a10eae51"}, "_deposit": {"created_by": 3, "id": "2456", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "2456"}, "status": "published"}, "_oai": {"id": "oai:toyama.repo.nii.ac.jp:00002456", "sets": ["442"]}, "author_link": ["6029", "155550"], "item_2_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2005", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "suppl.", "bibliographicPageEnd": "144", "bibliographicPageStart": "138", "bibliographicVolumeNumber": "22", "bibliographic_titles": [{"bibliographic_title": "和漢医薬学雑誌 = Journal of traditional medicines"}]}]}, "item_2_description_15": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We summarized the flow of our research on the development of antiviral traditional medicines, which was a collaboration with the late Professor Tsuneo Namba. Even if traditional medicines and compounds purified from them have strong antiviral activity in vitro, we believe they are just inhibitors and not medicines if they have no therapeutic efficacy in vivo. Therefore our study is based on the confirmation of the oral therapeutic efficacy with traditional dosages in humans. We first screened the in vitro-antiviral activity of typically and easily available traditional medicines that are currently used for the treatment of various chronic diseases in China, India and Japan. Then we selected the extracts of traditional medicines with prophylactic and therapeutic antiviral activity in animal infection models. By verifying the antiviral activity of extracts in vivo, their new indications for the use of viral infection would be established. In consequence, the drinking of the extracts of traditional medicines like a daily tea or coffee may be used as prophylaxis and therapy for diseases caused by viral infection and improve the quality of life. Here, we describe how the antiviral extracts of traditional medicines and active compounds involved in them were explored and characterized, based on a view that antiviral activity should be active in vivo.", "subitem_description_type": "Abstract"}]}, "item_2_description_40": {"attribute_name": "資源タイプ(DSpace)", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "和漢医薬学会"}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "rights: 本文データは和漢医薬学会の許諾に基づきCiNiiから複製したものである"}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA12035198", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_8": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "18801447", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kurokawa, Masahiko"}], "nameIdentifiers": [{"nameIdentifier": "155550", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shiraki, Kimiyasu"}], "nameIdentifiers": [{"nameIdentifier": "6029", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000050135745", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/1000050135745"}, {"nameIdentifier": "50135745", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000050135745"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-02-15"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "wakan05-suppl138.pdf", "filesize": [{"value": "989.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 989400.0, "url": {"label": "wakan05-suppl138.pdf", "url": "https://toyama.repo.nii.ac.jp/record/2456/files/wakan05-suppl138.pdf"}, "version_id": "8ad7d0e2-1a48-44a6-a900-e67e0d413019"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Antiviral activity", "subitem_subject_scheme": "Other"}, {"subitem_subject": "traditional medicines", "subitem_subject_scheme": "Other"}, {"subitem_subject": "herpes simplex virus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cytomegalovirus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "prophylactic treatment", "subitem_subject_scheme": "Other"}, {"subitem_subject": "therapeutic treatment", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "New antiviral agents from traditional medicines(Chemical \u0026 Pharmacological study)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "New antiviral agents from traditional medicines(Chemical \u0026 Pharmacological study)"}]}, "item_type_id": "2", "owner": "3", "path": ["442"], "permalink_uri": "http://hdl.handle.net/10110/2318", "pubdate": {"attribute_name": "公開日", "attribute_value": "2008-02-14"}, "publish_date": "2008-02-14", "publish_status": "0", "recid": "2456", "relation": {}, "relation_version_is_last": true, "title": ["New antiviral agents from traditional medicines(Chemical \u0026 Pharmacological study)"], "weko_shared_id": 3}