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Calcification inhibitors in human ligamentum flavum
https://doi.org/10.11501/3087115
https://doi.org/10.11501/3087115207fe167-322c-4fdb-b7aa-9c56c3000e1c
名前 / ファイル | ライセンス | アクション |
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000000247304.pdf (7.5 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2013-02-07 | |||||
タイトル | ||||||
タイトル | Calcification inhibitors in human ligamentum flavum | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Human ligamentum flavum | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Calcification | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Calcification inhibitors | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
ID登録 | ||||||
ID登録 | 10.11501/3087115 | |||||
ID登録タイプ | JaLC | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
丸田, 喜美子
× 丸田, 喜美子 |
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著者別名 | ||||||
姓名 | Maruta, Kimiko | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | ヒト黄色靱帯における石灰化抑制因子 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | To examine the presence of substances which inhibit calcification in human ligamentum flavum, the calcification inhibitory effect of human ligamentum flavum extract obtained by extraction of the tissue with 3% Na_2HPO_4 was determined by the in vitro calcium uptake of the ligamentum flavum matrix. In addition, grafts of extracted and non-extracted dry ligamentum flavum matrices were transplanted into the dorsal muscles of rats, and calcification in the grafts was examined radiologically and histochemically. In order to determine whether or not component cells of human ligamentum flavum produce calcification inhibitors, ligamentum flavum cells were cultured, and thecrystal inhibitor activity of the culture medium was measured by the seed test using hydroxyapatite as the nucleus of precipitation. The calcification reaction system demonstrated that the ligamentum flavum extract contains an inhibitory factor for calcium uptake by the ligamentum flavum matrix. The seed test revealed that human ligamentum flavum cells produce calcification inhibitor activity. The inhibitor activity was fractionated into two peaks by gel filtration of the culture medium. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 富山医科薬科大学・医学博士・乙第144号・丸田喜美子・1991/10/9 | |||||
書誌情報 | 発行日 1991-10-09 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13202 | |||||
学位授与機関名 | 富山医科薬科大学 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 1991-10-09 | |||||
学位授与番号 | ||||||
学位授与番号 | 乙第144号 |