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As controls, 13 non-VDT workers received no supplementation (Group A). Twenty-six VDT workers were randomized into 2 groups: Group B consisted of 13 subjects who received oral astaxanthin, 5 mg/day, for 4 weeks, and Group C consisted of 13 subjects who received an oral placebo, 5 mg/day, for 4 weeks. No significant difference in age was noted among the 3 groups. A double-masked study was designed in Groups B and C. Accommodation amplitude in Group A was 3.7± 1.5 diopters. Accommodation amplitudes (2.3±1.4 and 2.2±1.0 diopters) in Groups B and C before supplementation were significantly (p\u003c0.05) lower than in Group A. Accommodation amplitude (2.8±1.6 diopters) in Group B after astaxanthin treatment was significantly (p\u003c0.01) larger than before supplementation, while accommodation amplitude (2.3±1.1 diopters) in Group C after placebo supplementation was unchanged. The CFFs and amplitude and latency of P100 in PVEP in Group A were 45.0±4.2 Hz, 6.5±1.8μV, and 101.3±6.5 msec, respectively. The CFFs in Groups B and C before supplementation were significantly (p\u003c0.05) lower than in Group A. The CCFs in Groups B and C did not change after supplementation. Amplitudes and latencies of P100 in PVEP in Groups B and C before supplementation were similar to those in Group A and did not change after supplementation. Findings of the present study indicated that accommodation amplitude improved after astaxanthin supplementation in VDT workers.\n 赤色カロチノイドの一種であるアスタキサンチンのvisual display terminal(VDT)作業者の調節力,中心フリッカー値,パターン視覚誘発電位に及ぼす影響を調べた。VDT作業を行わない13人をコントロールとした(Group A)。26人のVDT作業者を2群に無作為に分けた。Group Bはアスタキサンチン一日5mg 4週間内服した13人で,Group Cはアスタキサンチンを含有しないカプセルを4週間内服した13人とした。外見上同じカプセルでの内服投与を行った。結果:Group AはGroup B及びGroup Cと比較して,調節力,中心フリッカー値は有意に高い値であったが,パターン視覚誘発電位検査結果は,Group B,Cと有意差はなかった。Group Bでは,アスタキサンチンの投与前後で有意な調節力の改善がみられた(p\u003c0.01)。しかし,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。Group Cでは,投与前後で,調節力,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。考察:VDT作業者では,非作業者と比べ調節力,中心フリッカー値が低下していることは以前より報告されており,今回の我々の研究でも同様の結果であった。VDT作業者で,アスタキサンチン非内服群では,調節力は投与前後で変化がなかったが,アスタキサンチンの内服群で,有意に調節力が改善した。VDT作業者の調節力の改善には,アスタキサンチンの内服が有効と考えられた。", "subitem_description_type": "Abstract"}]}, "item_2_description_40": {"attribute_name": "資源タイプ(DSpace)", "attribute_value_mlt": [{"subitem_description": "Article", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "和漢医薬学会"}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "rights: 本文データは和漢医薬学会の許諾に基づき複製したものである"}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN10486121", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_8": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "13406302", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nagaki, Yasunori"}], "nameIdentifiers": [{"nameIdentifier": "132365", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hayasaka, Seiji"}], "nameIdentifiers": [{"nameIdentifier": "132366", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamada, Tetsuya"}], "nameIdentifiers": [{"nameIdentifier": "132367", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hayasaka, Yuriko"}], "nameIdentifiers": [{"nameIdentifier": "132368", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sanada, Mari"}], "nameIdentifiers": [{"nameIdentifier": "132369", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uonomi, Takatoshi"}], "nameIdentifiers": [{"nameIdentifier": "132370", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-02-15"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "20020503.pdf", "filesize": [{"value": "591.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 591600.0, "url": {"label": "20020503.pdf", "url": "https://toyama.repo.nii.ac.jp/record/2207/files/20020503.pdf"}, "version_id": "377b9359-4bef-4474-80c9-ad0432856f4a"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "accommodation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "astaxanthin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "visual display terminal", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers"}]}, "item_type_id": "2", "owner": "3", "path": ["442"], "permalink_uri": "http://hdl.handle.net/10110/1927", "pubdate": {"attribute_name": "公開日", "attribute_value": "2008-01-24"}, "publish_date": "2008-01-24", "publish_status": "0", "recid": "2207", "relation": {}, "relation_version_is_last": true, "title": ["Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers"], "weko_shared_id": -1}
Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers
http://hdl.handle.net/10110/1927
http://hdl.handle.net/10110/1927db55280b-995d-47f5-b481-88ad2b8a4062
名前 / ファイル | ライセンス | アクション |
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20020503.pdf (591.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-01-24 | |||||
タイトル | ||||||
タイトル | Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | accommodation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | astaxanthin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | visual display terminal | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Nagaki, Yasunori
× Nagaki, Yasunori× Hayasaka, Seiji× Yamada, Tetsuya× Hayasaka, Yuriko× Sanada, Mari× Uonomi, Takatoshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We evaluated the effects of astaxanthin, a red carotenoid, on accommodation, critical flicker fusion (CFF), and pattern visual evoked potential (PVEP) in visual display terminal (VDT) workers. As controls, 13 non-VDT workers received no supplementation (Group A). Twenty-six VDT workers were randomized into 2 groups: Group B consisted of 13 subjects who received oral astaxanthin, 5 mg/day, for 4 weeks, and Group C consisted of 13 subjects who received an oral placebo, 5 mg/day, for 4 weeks. No significant difference in age was noted among the 3 groups. A double-masked study was designed in Groups B and C. Accommodation amplitude in Group A was 3.7± 1.5 diopters. Accommodation amplitudes (2.3±1.4 and 2.2±1.0 diopters) in Groups B and C before supplementation were significantly (p<0.05) lower than in Group A. Accommodation amplitude (2.8±1.6 diopters) in Group B after astaxanthin treatment was significantly (p<0.01) larger than before supplementation, while accommodation amplitude (2.3±1.1 diopters) in Group C after placebo supplementation was unchanged. The CFFs and amplitude and latency of P100 in PVEP in Group A were 45.0±4.2 Hz, 6.5±1.8μV, and 101.3±6.5 msec, respectively. The CFFs in Groups B and C before supplementation were significantly (p<0.05) lower than in Group A. The CCFs in Groups B and C did not change after supplementation. Amplitudes and latencies of P100 in PVEP in Groups B and C before supplementation were similar to those in Group A and did not change after supplementation. Findings of the present study indicated that accommodation amplitude improved after astaxanthin supplementation in VDT workers. 赤色カロチノイドの一種であるアスタキサンチンのvisual display terminal(VDT)作業者の調節力,中心フリッカー値,パターン視覚誘発電位に及ぼす影響を調べた。VDT作業を行わない13人をコントロールとした(Group A)。26人のVDT作業者を2群に無作為に分けた。Group Bはアスタキサンチン一日5mg 4週間内服した13人で,Group Cはアスタキサンチンを含有しないカプセルを4週間内服した13人とした。外見上同じカプセルでの内服投与を行った。結果:Group AはGroup B及びGroup Cと比較して,調節力,中心フリッカー値は有意に高い値であったが,パターン視覚誘発電位検査結果は,Group B,Cと有意差はなかった。Group Bでは,アスタキサンチンの投与前後で有意な調節力の改善がみられた(p<0.01)。しかし,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。Group Cでは,投与前後で,調節力,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。考察:VDT作業者では,非作業者と比べ調節力,中心フリッカー値が低下していることは以前より報告されており,今回の我々の研究でも同様の結果であった。VDT作業者で,アスタキサンチン非内服群では,調節力は投与前後で変化がなかったが,アスタキサンチンの内服群で,有意に調節力が改善した。VDT作業者の調節力の改善には,アスタキサンチンの内服が有効と考えられた。 |
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書誌情報 |
和漢医薬学雑誌 = Journal of traditional medicines 巻 19, 号 5, p. 170-173, 発行日 2002-10 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13406302 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10486121 | |||||
権利 | ||||||
権利情報 | rights: 本文データは和漢医薬学会の許諾に基づき複製したものである | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 和漢医薬学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |