{"created":"2023-07-25T09:04:22.541205+00:00","id":2207,"links":{},"metadata":{"_buckets":{"deposit":"3c58153e-b685-4860-b32d-80f79f6e2f1d"},"_deposit":{"created_by":3,"id":"2207","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2207"},"status":"published"},"_oai":{"id":"oai:toyama.repo.nii.ac.jp:00002207","sets":["439:440:441:442"]},"author_link":["132368","132367","132370","132365","132369","132366"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"173","bibliographicPageStart":"170","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"和漢医薬学雑誌 = Journal of traditional medicines"}]}]},"item_2_description_15":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We evaluated the effects of astaxanthin, a red carotenoid, on accommodation, critical flicker fusion (CFF), and pattern visual evoked potential (PVEP) in visual display terminal (VDT) workers. As controls, 13 non-VDT workers received no supplementation (Group A). Twenty-six VDT workers were randomized into 2 groups: Group B consisted of 13 subjects who received oral astaxanthin, 5 mg/day, for 4 weeks, and Group C consisted of 13 subjects who received an oral placebo, 5 mg/day, for 4 weeks. No significant difference in age was noted among the 3 groups. A double-masked study was designed in Groups B and C. Accommodation amplitude in Group A was 3.7± 1.5 diopters. Accommodation amplitudes (2.3±1.4 and 2.2±1.0 diopters) in Groups B and C before supplementation were significantly (p<0.05) lower than in Group A. Accommodation amplitude (2.8±1.6 diopters) in Group B after astaxanthin treatment was significantly (p<0.01) larger than before supplementation, while accommodation amplitude (2.3±1.1 diopters) in Group C after placebo supplementation was unchanged. The CFFs and amplitude and latency of P100 in PVEP in Group A were 45.0±4.2 Hz, 6.5±1.8μV, and 101.3±6.5 msec, respectively. The CFFs in Groups B and C before supplementation were significantly (p<0.05) lower than in Group A. The CCFs in Groups B and C did not change after supplementation. Amplitudes and latencies of P100 in PVEP in Groups B and C before supplementation were similar to those in Group A and did not change after supplementation. Findings of the present study indicated that accommodation amplitude improved after astaxanthin supplementation in VDT workers.\n 赤色カロチノイドの一種であるアスタキサンチンのvisual display terminal(VDT)作業者の調節力,中心フリッカー値,パターン視覚誘発電位に及ぼす影響を調べた。VDT作業を行わない13人をコントロールとした(Group A)。26人のVDT作業者を2群に無作為に分けた。Group Bはアスタキサンチン一日5mg 4週間内服した13人で,Group Cはアスタキサンチンを含有しないカプセルを4週間内服した13人とした。外見上同じカプセルでの内服投与を行った。結果:Group AはGroup B及びGroup Cと比較して,調節力,中心フリッカー値は有意に高い値であったが,パターン視覚誘発電位検査結果は,Group B,Cと有意差はなかった。Group Bでは,アスタキサンチンの投与前後で有意な調節力の改善がみられた(p<0.01)。しかし,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。Group Cでは,投与前後で,調節力,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。考察:VDT作業者では,非作業者と比べ調節力,中心フリッカー値が低下していることは以前より報告されており,今回の我々の研究でも同様の結果であった。VDT作業者で,アスタキサンチン非内服群では,調節力は投与前後で変化がなかったが,アスタキサンチンの内服群で,有意に調節力が改善した。VDT作業者の調節力の改善には,アスタキサンチンの内服が有効と考えられた。","subitem_description_type":"Abstract"}]},"item_2_description_40":{"attribute_name":"資源タイプ(DSpace)","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"和漢医薬学会"}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"rights: 本文データは和漢医薬学会の許諾に基づき複製したものである"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10486121","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13406302","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nagaki, Yasunori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayasaka, Seiji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamada, Tetsuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayasaka, Yuriko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sanada, Mari"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uonomi, Takatoshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-15"}],"displaytype":"detail","filename":"20020503.pdf","filesize":[{"value":"591.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20020503.pdf","url":"https://toyama.repo.nii.ac.jp/record/2207/files/20020503.pdf"},"version_id":"377b9359-4bef-4474-80c9-ad0432856f4a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"accommodation","subitem_subject_scheme":"Other"},{"subitem_subject":"astaxanthin","subitem_subject_scheme":"Other"},{"subitem_subject":"visual display terminal","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers"}]},"item_type_id":"2","owner":"3","path":["442"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-01-24"},"publish_date":"2008-01-24","publish_status":"0","recid":"2207","relation_version_is_last":true,"title":["Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-25T16:39:57.552742+00:00"}