{"created":"2023-07-25T09:06:59.200516+00:00","id":5273,"links":{},"metadata":{"_buckets":{"deposit":"f316970b-8f19-4ffa-9330-cf983d3377ac"},"_deposit":{"created_by":3,"id":"5273","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"5273"},"status":"published"},"_oai":{"id":"oai:toyama.repo.nii.ac.jp:00005273","sets":["646:647:648"]},"author_link":["159202","159206","159207","159201","159203","159205","159204"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"50","bibliographicPageStart":"45","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"和漢医薬学雑誌 = Journal of traditional medicines"}]}]},"item_2_description_15":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"沱茶は中国雲南省のアッサム茶の葉を蒸して作られる緊圧茶で,抗老化,コレステロール低下,免疫増強,血圧降下等の作用があると言われている。我々は,DPPHラジカル捕捉活性を指標として成分検索を行ない,得られた成分についてDPPHラジカル捕捉活性と共にD-GalN/TNF-α誘発マウス肝細胞死阻害活性を測定した。その結果,沱茶がフェノール類,リグナン,フラボノイド,フラバン3オール類などの抗酸化成分を多く含む事を明らかにし,それら成分の構造と活性との関係について考察した。\n Tuocha is one of the special varieties of fermented compressed tea leaves, praised for its important health benefits, such as anti-aging, lowering cholesterol, enhancing immune function, lowering of blood pressure, reducing heart attacks etc. In the present study, we carried out fractionation and isolation of the active constituents, guided by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. In addition, antioxidative and antihepatotoxic potency on D-galactosamine (D-GalN)/tumor necrosis factor-alpha (TNF-α)-induced cell death in primary cultured mouse hepatocytes was also examined. Our study revealed that, tuocha is rich in antioxidants such as phenolics, lignans, flavanoides and flavan-3-ols, and showed a good understanding between structure and activity relationship.","subitem_description_type":"Abstract"}]},"item_2_description_40":{"attribute_name":"資源タイプ(DSpace)","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"159207","nameIdentifierScheme":"WEKO"}],"names":[{"name":"門田, 重利"}]}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"和漢医薬学会"}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"rights: 本文データは和漢医薬学会の許諾に基づき複製したものである"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10486121","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1340-6302","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"AWALE, Suresh"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Wang, Shumin"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tezuka, Yasuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"BANSKOTA, ArjunH."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TRAN, QuanLe"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kadota, Shigetoshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"20030201.pdf","filesize":[{"value":"886.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20030201.pdf","url":"https://toyama.repo.nii.ac.jp/record/5273/files/20030201.pdf"},"version_id":"e891f4cd-2897-4e6e-b22b-bfe5ee003b8d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Tuocha","subitem_subject_scheme":"Other"},{"subitem_subject":"DPPH free radical scavenging activity","subitem_subject_scheme":"Other"},{"subitem_subject":"hepatoprotective activity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Antioxidative and antihepatotoxic principles of Tuocha","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Antioxidative and antihepatotoxic principles of Tuocha"}]},"item_type_id":"2","owner":"3","path":["648"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-01-23"},"publish_date":"2008-01-23","publish_status":"0","recid":"5273","relation_version_is_last":true,"title":["Antioxidative and antihepatotoxic principles of Tuocha"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-11-06T04:44:21.004118+00:00"}