@article{oai:toyama.repo.nii.ac.jp:00005250,
 author = {Midorikawa, Kiyoshi and BANSKOTA, ArjunH. and Tezuka, Yasuhiro and Matsushige, Katsumichi and MESSAGE, Dejair and HUERTAS, AlfredoA.G. and Kadota, Shigetoshi},
 issue = {5},
 journal = {和漢医薬学雑誌 = Journal of traditional medicines},
 month = {Oct},
 note = {application/pdf, Liquid chromatography mass-spectrometry (LC-MS) analysis of Brazilian propolis and the leaves, buds, stem and flowers of Baccharis dracunculifolia were performed. The water extracts of propolis and B. dracunculifolia both contain 3,4-di-O-caffeoylquinic acid (28), 3,5-di-O-caffeoylquinic acid (31) and chlorogenic acid (32). The intensities of 28 and 31 in the water extract of the buds were stronger than the other parts, suggesting that the buds of B. dracunculifolia should be potent source of these caffeoylquinic acids. Moreover, 27 individual compounds including labdane-type diterpenes, prenylated compounds, flavonoids and other phenolics which were previously isolated from Brazilian propolis, were also identified in the MeOH extract of B. dracunculifolia. Among them, 24 compounds were detected in the buds alone, indicating that it should be an important source of Brazilian propolis. The botanical origin of 19 components of Brazilian propolis was, for the first time, established to be B. dracunculifolia.
 ブラジル産プロポリス及びBaccharis dracunculifoliaの葉,新芽,茎,花についてLC-MS分析を行なった。プロポリス及びB. dracunculifoliaの水エキスは共に3,4-di-O-caffeoylquinic acid (28), 3,5-di-O-caffeoylquinicacid (31), chlorogenic acid (32)を含んでいた。化合物28及び31は新芽部分の水エキスが他の部分のエキスよりも強度が強く,B. dracunculifoliaの新芽部分がこれらcaffeoylquinic acidsの重要な起源である事が示唆された。さらに,ブラジル産プロポリスの成分として報告のあるラブダン型ジテルペン,プレニル化合物,フラボノイド,桂皮酸誘導体など27化合物をB. dracunculifoliaのメタノールエキス中に同定した。これら化合物中,24化合物が新芽部分のエキスにのみ検出された事も,B. dracunculifoliaの新芽部分がブラジル産プロポリスの重要な起源である事を示唆している。ブラジル産プロポリスの19化合物の植物起源については,今回初めて明らかになった。, Article},
 pages = {187--194},
 title = {Buds of Baccharis dracunculifolia : potent source of biologically active caffeoylquinic acids and labdane-type diterpenes of Brazilian propolis},
 volume = {20},
 year = {2003}
}