@article{oai:toyama.repo.nii.ac.jp:00005247,
 author = {Shibahara, Naotoshi},
 issue = {1},
 journal = {和漢医薬学雑誌 = Journal of traditional medicines},
 month = {Feb},
 note = {application/pdf, In order to clarify the correlation between "oketsu" syndrome and autonomic nervous activity, subjects were evaluated with laser Doppler flowmetry and spectral analyses of R-R intervals (RRs) and systolic blood pressure (SBP). According to the diagnostic criteria of "oketsu", the "oketsu" score (OS) was evaluated. In a sectional study, the results showed that a significant decrease in skin blood flow (SBF) was observed in proportion to the severity of the "oketsu" state, and the low-frequency component of SBP (SBP-LF) in the "oketsu" state was significantly larger than that in the non-"oketsu" state. In a diachronic study, the changes in OS and the parameters between week 0 and 12 weeks later were investigated, with the quantity of each change being calculated as Δ-. Δ-SBF showed a significant negative correlation with Δ-OS, and Δ-RR-L/H, Δ-SBP-LF and Δ-SBP-L/H revealed significant positive correlations with Δ-OS. It is known that SBF changes with sympathetic nervous activity, and SBP-LF and SBP-L/H reflect α-sympathetic nervous activity. These results suggest that α-sympathetic nervous activity increased in the "oketsu" state, and this significant relationship was maintained even after change in the "oketsu" state.
瘀(オ)血病態と自律神経活動との関連性を明らかとするために,レーザードプラ血流計,R-R間隔と収縮期血圧のスペクトル解析を用いて検討した。各対象者について瘀血診断基準により瘀血スコアを算出した。断面的検討では,皮膚血流量(SBF)は瘀血病態の重症化とともに減少し,収縮期血圧低周波数成分(SBP-LF)は軽度及び重度瘀血群が非瘀血群に比較して有意に高値を示した。経時的検討では,SBFの変化量は瘀血スコアと負の相関を示し,R-R間隔成分比(RR-L/H)・収縮期血圧低周波成分(SBP-LF)・収縮期血圧成分比(SBP-L/H)の変化量は瘀血スコアと正の相関を示した。SBFは交感神経活動にともない変化し,SBP-LFはα作動性交感神経活動と関連するとされている。今回の結果は、瘀血病態がα作動性交感神経活動と密接に関連していることを示唆するものである。, Article},
 pages = {1--6},
 title = {Correlation between "oketsu" syndrome and autonomic nervous activity},
 volume = {21},
 year = {2004}
}