{"created":"2023-07-25T09:06:57.245916+00:00","id":5237,"links":{},"metadata":{"_buckets":{"deposit":"846cc480-08cb-49e9-a1b1-e86221f0c51d"},"_deposit":{"created_by":3,"id":"5237","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"5237"},"status":"published"},"_oai":{"id":"oai:toyama.repo.nii.ac.jp:00005237","sets":["646:647:648"]},"author_link":["7991","158988","158998","159001","158989","158986","158993","5921","158997","158990","158994","8047","158995"],"item_2_alternative_title_19":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Effects of a new original formulation containing crude drugs used for self-medication on model animals with lifestyle related disease"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"204","bibliographicPageStart":"199","bibliographicVolumeNumber":"21","bibliographic_titles":[{"bibliographic_title":"和漢医薬学雑誌 = Journal of traditional medicines"}]}]},"item_2_description_15":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_31":{"attribute_name":"スポンサー","attribute_value_mlt":[{"subitem_description":"21st Century COE Program, Toyama Medical and Pharmaceutical University","subitem_description_type":"Other"}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A new original formulation containing crude drugs used for self-medication was developed by a joint project of the Federation of Pharmaceutical Inductries Association in Toyama, Toyama Prefecture (Toyama Prefectural Institute for Pharmaceutical Research) and Toyama Medical and Pharmaceutical University. This formulation consists of 11 crude drugs. In this study, the effect of this formulation on model animals with a life-style related disease was studied. Spontaneously hypertensive rats added to hypercholesterol diet were given this formulation in chow for 8 weeks. The results indicated that this formulation caused a decrease in vasocontraction induced by phospholipase A2. Plasma triglyceride and lipid peroxide were significantly decreased, but blood pressure was not changed. Furthermore spontaneously diabetic rats were given this formulation in chow for 4 weeks. The results indicated that this formulation caused a decrease in plasma triglyceride, lipid peroxide and fibrinogen significantly, but blood glucose was not changed. From these results, it was supposed that this formulation exerted the suppression effect of vasocontraction, improvement effect of fatty metabolism and decrease effect of fibrinogen. This formulation is thought to be a useful drug to prevent the vasocomplication based on life-style related disease.","subitem_description_type":"Abstract"}]},"item_2_description_40":{"attribute_name":"資源タイプ(DSpace)","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"158995","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Goto, Hirozo"}]},{"nameIdentifiers":[{"nameIdentifier":"5921","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000080251891","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/1000080251891"},{"nameIdentifier":"80251891","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000080251891"}],"names":[{"name":"Shimada, Yutaka"}]},{"nameIdentifiers":[{"nameIdentifier":"158997","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sekiya, Nobuyasu"}]},{"nameIdentifiers":[{"nameIdentifier":"158998","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Hikiami, Hiroaki"}]},{"nameIdentifiers":[{"nameIdentifier":"8047","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30324049","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000030324049"}],"names":[{"name":"Sakai, Shinya"}]},{"nameIdentifiers":[{"nameIdentifier":"7991","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10272907","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000010272907"}],"names":[{"name":"Shibahara, Naotoshi"}]},{"nameIdentifiers":[{"nameIdentifier":"159001","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Terasawa, Katsutoshi"}]}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"和漢医薬学会"}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである"}]},"item_2_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12035198","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1880-1447","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"後藤, 博三"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"嶋田, 豊"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"谿, 忠人"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"関矢, 信康"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"引網, 宏彰"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"酒井, 伸也"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"柴原, 直利"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"寺澤, 捷年"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tani, Tadato"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-17"}],"displaytype":"detail","filename":"wakan04-goto.pdf","filesize":[{"value":"708.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"wakan04-goto.pdf","url":"https://toyama.repo.nii.ac.jp/record/5237/files/wakan04-goto.pdf"},"version_id":"7eb15199-daf5-4d50-8898-7319e9d9f558"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"a new original formulation containing crude drugs use for self-medication","subitem_subject_scheme":"Other"},{"subitem_subject":"life-style related disease","subitem_subject_scheme":"Other"},{"subitem_subject":"spontaneously hypertensive rats","subitem_subject_scheme":"Other"},{"subitem_subject":"spontaneously diabetic rats","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"富山オリジナルブランド配置薬の生活習慣病モデル動物に対する効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"富山オリジナルブランド配置薬の生活習慣病モデル動物に対する効果"}]},"item_type_id":"2","owner":"3","path":["648"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-12-17"},"publish_date":"2007-12-17","publish_status":"0","recid":"5237","relation_version_is_last":true,"title":["富山オリジナルブランド配置薬の生活習慣病モデル動物に対する効果"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-11-06T04:44:34.532314+00:00"}