@article{oai:toyama.repo.nii.ac.jp:00005218,
 author = {GAO, JiangJing and Hattori, Masao},
 issue = {4},
 journal = {和漢医薬学雑誌 = Journal of traditional medicines},
 month = {Aug},
 note = {application/pdf, 21st Century COE Program, Toyama Medical and Pharmaceutical University, ヒト腸内細菌は広く自然界に存在する植物エストロゲンの前駆体の代謝活性化に必須である。本総説ではin vitroの実験に基づいた植物エストロゲン前駆体secoisolariciresinol diglucoside (SDG), arctiin, pinoresinol diglucoside (PDG)やそれらのアグリコンの動物リグナン, enterodiol (END), enterolactone (ENL)への変換に関する最近の研究成果を概説している。また, これら関連反応に関与する腸内細菌の単離や性質についても言及している。
The role of human intestinal bacteria is indispensable for the metabolic activation of phytoestrogenic precursor lignans. This review summarized recent researches on the in vitro intestinal bacteria transformation of lignan precursors, secoisolariciresinol diglucoside (SDG), arctiin, pinoresinol diglucoside (PDG), and their aglycones, to mammalian lignans enterodiol (END) and enterolactone (ENL). The isolation and characterization of several bacteria from human feces, responsible for the related reactions were also described., Article},
 pages = {213--221},
 title = {Metabolic activation of lignans to estrogenic and antiestrogenic substances by human intestinal bacteria},
 volume = {22},
 year = {2005}
}