@article{oai:toyama.repo.nii.ac.jp:00005217, author = {Kimura, Ikuko and Tsuneki, Hiroshi}, issue = {1}, journal = {和漢医薬学雑誌 = Journal of traditional medicines}, month = {Feb}, note = {application/pdf, 漢方方剤やアユルベーダ薬の薬理作用における, 修治, 相乗作用, 組み合わせの科学的根拠を明らかにするため, 著者らによる公表論文の実験データを用いて, 数式による理論化を試みた。 The formulations of traditional medicines used in China, India and Japan have been constructed to expect desirable treatment of diseases. The principles are based on the interaction of several crude drugs or several ingredients even in a single crude drug. Therefore, the apparent combined effects are equivalent to the sum of effects of those components which underwent addition, potentiation, subtraction and modulation. Here we provide hypothetical mathematical formulas to explain the theory of combinatorics, which successfully proved the pharmacological effects of processed single herbs and the basis of polyherbal therapies. The constructed formulas will contribute to designing new formulations together with seeking novel patterns of pharmacological actions of traditional medicines or with understanding of the mechanisms behind them., Article}, pages = {1--3}, title = {Theoretical pharmacological effects in single herb and polyherbal therapies : influences of processing on the constituents, and their synergistic/modulatory interactions}, volume = {22}, year = {2005} }