{"created":"2023-07-25T09:04:38.407560+00:00","id":2513,"links":{},"metadata":{"_buckets":{"deposit":"7b9d4735-e2a1-4dab-95a6-445e0015ad38"},"_deposit":{"created_by":3,"id":"2513","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2513"},"status":"published"},"_oai":{"id":"oai:toyama.repo.nii.ac.jp:00002513","sets":["439:440:443:444:446"]},"author_link":["156058","156053","156054","156052","156057","156056","156055","156051"],"item_3_alternative_title_19":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Study on the antiseptics-associated changes in physiological conditions of skin surface"}]},"item_3_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"58","bibliographicPageStart":"49","bibliographicVolumeNumber":"2","bibliographic_titles":[{"bibliographic_title":"富山医科薬科大学看護学会誌"}]}]},"item_3_description_15":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"消毒剤の皮膚刺激性を成人30名の前腕の皮膚を用いて検討した.臨床で繁用される消毒剤の調査結果をもとに, ポビドンヨード製剤(PVP-1), 日局消毒用エタノール(EtOH), グルコン酸クロルヘキシジン製剤(CHG), およびチオ硫酸ナトリウム製剤(STS)を選択し, 対照群として生理的食塩水(SCI)を用いた.消毒剤塗布部に加え無処理の皮膚において, 単回及び一週間の連続使用後の皮膚表面のpH, 角質水分量, 経表皮水分喪失量, 皮表皮脂量の生理機能の変化を多角的に検討し, 皮膚刺激の調査も加えた.健康な皮膚の表面はpH5.5～7.0であり, 今回使用した消毒剤のうちPVP-I, CHGの塗布部では低値を示し, STSの塗布部では高値を示していたが, pHはいずれにおいても生理的中性範囲内に留まり, 消毒剤の刺激に対する皮膚の緩衝作用が有効に働いていた.肉眼的皮膚刺激, 皮表皮脂量は, どの薬剤も有意差は認められなかったが, 消毒剤一週間連続使用後のPVP-I, EtOH, CHG塗布部においては, 角質水分量が低値を示し, 皮膚刺激が長期にわたると角質水分保持能が低下する可能性が示唆された.","subitem_description_type":"Abstract"},{"subitem_description":"This study was conducted to examine antiseptics-associated changes in physiological conditions of skin surface. When povidone-iodine (PVP-I), ethanol (EtOH), sodium thiosulfate (STS), chlorhexidine gluconate (CHG) and sodium chloride irrigation (SCI) were applied at appropriate concentrations to both foramrs of 30 volunteers of adult women twice a day (at the morning and evening) for one week, pH values of the skin surface were maintained within nomal ranges such as 5.5 to 7.0 before and after applications of agents either with a low pH (PVP-I and CHG) or high pH (STS). These data indicate that a buffer action of skin surface was not affected by the agents regardless of their pH values. Moeover, none of five agents induced significant changes in a self-assessed visual status (redness and irritation), and skin surface lipids before and after applications. However, stratum corneum hydration became lower levels after applications of PVP-1,EtOH and CHG. These results suggest that a long-term application (twice daily for one week) with PVP-1,EtOH or CHG might induce antisepices-associated skin disorders due to at least in part affecting on a water-holding capacity of stratum corneum.","subitem_description_type":"Abstract"}]},"item_3_description_40":{"attribute_name":"資源タイプ(DSpace)","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"156055","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tanaka, Aiko"}]},{"nameIdentifiers":[{"nameIdentifier":"156056","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Seki, Taisuke"}]},{"nameIdentifiers":[{"nameIdentifier":"156057","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ochiai, Hiroshi"}]},{"nameIdentifiers":[{"nameIdentifier":"156058","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tazawa, Kenji"}]}]},"item_3_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15099/00002507","subitem_identifier_reg_type":"JaLC"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"富山医科薬科大学看護学会"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11340152","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1344-1434","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田中, 愛子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"関, 太輔"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"落合, 宏"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田澤, 賢次"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-15"}],"displaytype":"detail","filename":"jns020006.pdf","filesize":[{"value":"998.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jns020006.pdf","url":"https://toyama.repo.nii.ac.jp/record/2513/files/jns020006.pdf"},"version_id":"3724e5a1-deb7-4b40-949f-ab3b0f863ebc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"消毒剤","subitem_subject_scheme":"Other"},{"subitem_subject":"成人皮膚","subitem_subject_scheme":"Other"},{"subitem_subject":"皮膚刺激性","subitem_subject_scheme":"Other"},{"subitem_subject":"皮膚生理機能","subitem_subject_scheme":"Other"},{"subitem_subject":"antiseptics-associated skin disorders","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"各種消毒剤の皮膚生理機能へ及ぼす影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"各種消毒剤の皮膚生理機能へ及ぼす影響"}]},"item_type_id":"3","owner":"3","path":["446"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-12-21"},"publish_date":"2007-12-21","publish_status":"0","recid":"2513","relation_version_is_last":true,"title":["各種消毒剤の皮膚生理機能へ及ぼす影響"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-25T15:54:30.595217+00:00"}