@article{oai:toyama.repo.nii.ac.jp:00002225, author = {Takaya, Yutaka and Shintani, Takahiro and Tahara, Eiichi and Tsukioka, Yasuyuki and Moriyama, Kenzo and Nakano, Kikuyo and Matsuda, Hideaki and Niizawa, Atsushi and Ninomiya, Hiroyuki and Goto, Hirozo and Shimada, Yutaka and Terasawa, Katsutoshi}, issue = {4}, journal = {和漢医薬学雑誌 = Journal of traditional medicines}, month = {Oct}, note = {application/pdf, Increasing evidence suggests that remnant-like lipoprotein particles cholesterol (RLP-C) is an independent cardio-vascular disease (CVD) risk factor. High levels of RLP-C exhibit findings similar to those of "oketsu" syndrome on blood rheology studies and scanning electron micrographs. We measured levels of RLP-C in plasma samples and "oketsu" scores obtained in 199 randomly selected subjects. The coefficient of correlation between levels of RLP-C and "oketsu" score was highly significant (r=0.581, P<0.0001). This finding suggests that presence of excess RLP-C in the blood resembles closely "oketsu" syndrome which we have shown to be an independent risk factor for CVD. レムナント様リポ蛋白コレステロール(RLP-C)が独立した心血管疾患(CVD)の危険因子であることが明らかになりつつある。RLP-Cが高値であると,血流動態上も電子顕微鏡像上でも瘀血病態と類似している。我々は無作為に選んだ199例より得られた血漿RLP-C値と瘀血スコアを測定した。RLP-C値と瘀血スコアの間には有意な相関が認められた(r=0.581,P<0.0001)。このことより,CVDに対する独立危険因子である高RLP-C血症が瘀血病態と酷似していることを示唆する結果となった。, Article}, pages = {147--150}, title = {Association of remnant-like lipoprotein particles cholesterol with "oketsu" syndrome}, volume = {23}, year = {2006} }