{"created":"2023-07-25T09:16:36.669628+00:00","id":16833,"links":{},"metadata":{"_buckets":{"deposit":"c87cfa3b-3b04-43f2-9d76-6b7f7fb2e72f"},"_deposit":{"created_by":17,"id":"16833","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"16833"},"status":"published"},"_oai":{"id":"oai:toyama.repo.nii.ac.jp:00016833","sets":["646:647:648"]},"author_link":["171218","47788","171219","171215","171217","171216"],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-07-26","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"271","bibliographicPageStart":"267","bibliographicVolumeNumber":"129","bibliographic_titles":[{"bibliographic_title":"Fitoterapia"}]}]},"item_2_description_15":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Two novel Lycopodium alkaloids, huperphlegmines A and B (1 and 2), were isolated from the aerial parts of Huperzia phlegmaria collected in Vietnam, together with the five known compounds lycophlegmariol A (3), phlegmariurine B (4), 5-hydroxymethyl-2-furaldehyde (5), rhemanone C (6), and loliolide (7). The chemical structures of the present compounds were elucidated by means of 1D and 2D NMR and HRESIMS spectroscopy, and by comparisons to the reported data in the literature. Compounds 1 and 2 showed moderate acetylcholinesterase inhibitory activities, with IC50 values of 25.95 ± 0.67 and 29.14 ± 0.77 μg/ml, respectively.","subitem_description_type":"Abstract"}]},"item_2_description_40":{"attribute_name":"資源タイプ(DSpace)","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1016/j.fitote.2018.07.016","subitem_relation_type_select":"DOI"}}]},"item_2_relation_42":{"attribute_name":"関係URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"出版社版"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.fitote.2018.07.016","subitem_relation_type_select":"DOI"}}]},"item_2_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0367-326X","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Niguyen, Hoai Thi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Doan, Huong Thi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ho, Duc Viet"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Pham, Ky Thanh"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Raal , Ain"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morita, Hiroyuki"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-26"}],"displaytype":"detail","filename":"Fitoterapia_129_267to271_Nguyen.pdf","filesize":[{"value":"297.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"Fitoterapia_129_267to271_Nguyen","url":"https://toyama.repo.nii.ac.jp/record/16833/files/Fitoterapia_129_267to271_Nguyen.pdf"},"version_id":"1fb380e1-0e03-4f02-adab-66155a299555"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Huperzia phlegmaria","subitem_subject_scheme":"Other"},{"subitem_subject":"Lycopodium alkaloid","subitem_subject_scheme":"Other"},{"subitem_subject":"huperphlegmine","subitem_subject_scheme":"Other"},{"subitem_subject":"acetylcholinesterase inhibitory activity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Huperphlegmines A and B, two novel Lycopodium alkaloids with an unprecedented skeleton from Huperzia phlegmaria, and their acetylcholinesterase inhibitory activities","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Huperphlegmines A and B, two novel Lycopodium alkaloids with an unprecedented skeleton from Huperzia phlegmaria, and their acetylcholinesterase inhibitory activities"}]},"item_type_id":"2","owner":"17","path":["648"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-07-26"},"publish_date":"2019-07-26","publish_status":"0","recid":"16833","relation_version_is_last":true,"title":["Huperphlegmines A and B, two novel Lycopodium alkaloids with an unprecedented skeleton from Huperzia phlegmaria, and their acetylcholinesterase inhibitory activities"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-11-06T04:44:34.156022+00:00"}