{"created":"2023-07-25T09:13:29.760249+00:00","id":12853,"links":{},"metadata":{"_buckets":{"deposit":"06d38c15-e362-4f19-99f8-11177e85100b"},"_deposit":{"created_by":3,"id":"12853","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"12853"},"status":"published"},"_oai":{"id":"oai:toyama.repo.nii.ac.jp:00012853","sets":["439:440:443:1480:1508"]},"author_link":["160533","160534"],"item_3_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1987-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"7","bibliographicPageStart":"5","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"富山医科薬科大学医学会誌"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ランゲルハンス細胞（LC）の歴史とランゲルハンス細胞頼粒（LCG）について概説した。次に正常ヒトではLC と特異的に反応するOKT6モノクローナル抗体がLCGと反応するかどうかを免疫電顕的に検討した。さらに， LCは異物を貪食することはよく知られているが，この異物貪食にLCGが関与するのかどうかについても電顕的に検討した。その結果， OKT6 は最初， LCの細胞膜と反応し時聞の経過とともに， 細胞膜が陥入し， さらに， 細胞質内に移動したLCGとも反応した。また， 異物摂取のtracerとして使用したhorseradish peroxidase (HRP）は， 細胞質内でLCGに摂取され，lysosomeに接するLCGはHRP陽性であった。これらの所見は， LCGが細胞膜由来であり，また異物摂取に関与していることを示唆するものである。","subitem_description_type":"Abstract"}]},"item_3_description_40":{"attribute_name":"資源タイプ(DSpace)","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_3_description_6":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"富山医科薬科大学医学会誌, 1(1), 1987.10, pp.05-07","subitem_description_type":"Other"}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"160534","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Takahashi, Shouzou"}]}]},"item_3_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15099/00015361","subitem_identifier_reg_type":"JaLC"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"富山医科薬科大学医学会"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10150743","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1349676X","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高橋, 省三"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-06-14"}],"displaytype":"detail","filename":"TMJ_001_OCR_Page005to007.pdf","filesize":[{"value":"2.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"TMJ_001_OCR_Page005to007.pdf","url":"https://toyama.repo.nii.ac.jp/record/12853/files/TMJ_001_OCR_Page005to007.pdf"},"version_id":"8970a9f8-9a2a-4e3b-a92a-ccfba093720d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ランゲルハンス細胞頼粒の生物学的意義について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ランゲルハンス細胞頼粒の生物学的意義について"}]},"item_type_id":"3","owner":"3","path":["1508"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-06-14"},"publish_date":"2016-06-14","publish_status":"0","recid":"12853","relation_version_is_last":true,"title":["ランゲルハンス細胞頼粒の生物学的意義について"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-25T15:51:20.190983+00:00"}