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Equality-evaluation of Wakan-yaku (Japanese-Chinese traditional medicines) with liquid chromatography-mass spectrometry (LC-MS) : comparison of constituents of original plants for Chinese traditional medicine "Dan-shen (Tan-j in)"
http://hdl.handle.net/10110/1946
http://hdl.handle.net/10110/194649561188-c65c-480a-b684-825641d5ef84
名前 / ファイル | ライセンス | アクション |
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20010201.pdf (1.2 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-01-24 | |||||
タイトル | ||||||
タイトル | Equality-evaluation of Wakan-yaku (Japanese-Chinese traditional medicines) with liquid chromatography-mass spectrometry (LC-MS) : comparison of constituents of original plants for Chinese traditional medicine "Dan-shen (Tan-j in)" | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Liquid chromatography-mass spectrometry (LC-MS) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | equality-evaluation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | qualityevaluation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tan-jin (Dan-shen, 丹参) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | genus Salvia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | aldose reductase inhibition | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tezuka, Yasuhiro
× Tezuka, Yasuhiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Wakan-yaku (Japanese-Chinese traditional medicines) are natural products and its constituents and/or activities depend on several factors, such as species, timing of collection, producing area, individual, etc. Thus, in order to use a homogeneous Wakan-yaku (Japanese-Chinese traditional medicines), it is necessary to use it with an evaluation on the equality of the constituents and/or activities of them, and the effective method for detecting the qualitative and/or quantitative change of the constituents and/or activities is required. However, almost all methods currently in use are based on the comparison of some representative constituents or activities and thus are not suitable for Wakan-yaku (Japanese-Chinese traditional medicines) which usually have many constituents and activities. On the other hand, application of gas chromatography-mass spectrometry (GC-MS) and liquid chromato-graphy-mass spectrometry (LC-MS) has recently been attempted, due to the possibility of measuring many compounds at once. This review deals with the LC-MS method, applicable to several types of compounds, by taking the case of our comparative study on the seventeen Salvia plants. 和漢薬は天然物であり,その成分や活性は種,採集時期,産地,個体等,種々の要因に依存する。そのため,均質な和漢薬を用いるには,その成分や活性の同等性を評価した上で用いる必要があり,成分含量や活性の変化を検出する有効な方法が必要とされている。しかし従来法の多くは,少数の代表的成分や活性の比較であり,多成分,多活性を有する和漢薬に適した方法ではなかった。一方,多成分の同時測定が可能なことから,ガスクロマトグラフィ連結質量分析計(GC-MS)や液体クロマトグラフィ連結質量分析計(LC-MS)の応用が近年試みられている。本稿では,種々のタイプの化合物に適応容易なLC-MS法について,我々が行なった漢薬"丹参"の基源植物間の比較を例として述べた。 |
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書誌情報 |
和漢医薬学雑誌 = Journal of traditional medicines 巻 18, 号 2, p. 39-47, 発行日 2001-04 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13406302 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10486121 | |||||
権利 | ||||||
権利情報 | rights: 本文データは和漢医薬学会の許諾に基づき複製したものである | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 和漢医薬学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |