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Antioxidative and antihepatotoxic principles of Tuocha
http://hdl.handle.net/10110/1908
http://hdl.handle.net/10110/19086f327ab4-85e6-4a42-8ef7-2f182669685e
名前 / ファイル | ライセンス | アクション |
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20030201.pdf (886.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-01-23 | |||||
タイトル | ||||||
タイトル | Antioxidative and antihepatotoxic principles of Tuocha | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tuocha | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | DPPH free radical scavenging activity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatoprotective activity | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
AWALE, Suresh
× AWALE, Suresh× Wang, Shumin× Tezuka, Yasuhiro× BANSKOTA, ArjunH.× TRAN, QuanLe× Kadota, Shigetoshi |
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著者別名 | ||||||
姓名 | 門田, 重利 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 沱茶は中国雲南省のアッサム茶の葉を蒸して作られる緊圧茶で,抗老化,コレステロール低下,免疫増強,血圧降下等の作用があると言われている。我々は,DPPHラジカル捕捉活性を指標として成分検索を行ない,得られた成分についてDPPHラジカル捕捉活性と共にD-GalN/TNF-α誘発マウス肝細胞死阻害活性を測定した。その結果,沱茶がフェノール類,リグナン,フラボノイド,フラバン3オール類などの抗酸化成分を多く含む事を明らかにし,それら成分の構造と活性との関係について考察した。 Tuocha is one of the special varieties of fermented compressed tea leaves, praised for its important health benefits, such as anti-aging, lowering cholesterol, enhancing immune function, lowering of blood pressure, reducing heart attacks etc. In the present study, we carried out fractionation and isolation of the active constituents, guided by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. In addition, antioxidative and antihepatotoxic potency on D-galactosamine (D-GalN)/tumor necrosis factor-alpha (TNF-α)-induced cell death in primary cultured mouse hepatocytes was also examined. Our study revealed that, tuocha is rich in antioxidants such as phenolics, lignans, flavanoides and flavan-3-ols, and showed a good understanding between structure and activity relationship. |
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書誌情報 |
和漢医薬学雑誌 = Journal of traditional medicines 巻 20, 号 2, p. 45-50, 発行日 2003-04 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1340-6302 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10486121 | |||||
権利 | ||||||
権利情報 | rights: 本文データは和漢医薬学会の許諾に基づき複製したものである | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 和漢医薬学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |