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Calcium dynamics and circadian rhythms in suprachiasmatic nucleus neurons
http://hdl.handle.net/10110/88
http://hdl.handle.net/10110/883fb3b460-e22c-4e57-9f05-a75c78c85a99
名前 / ファイル | ライセンス | アクション |
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Neuroscientist2003ikeda-final.pdf (4.2 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-04-27 | |||||
タイトル | ||||||
タイトル | Calcium dynamics and circadian rhythms in suprachiasmatic nucleus neurons | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Ca2+ homeostasis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Multiple-electrode-array-dish | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Period gene | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tetrodotoxin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Yellow cameleon | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ikeda, Masayuki
× Ikeda, Masayuki |
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著者別名 | ||||||
姓名 | 池田, 真行 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The hypothalamic suprachiasmatic nucleus (SCN) has a pivotal role in the mammalian circadian clock. SCN neurons generate circadian rhythms in action potential firing frequencies and neurotransmitter release, and the core oscillation is thought to be driven by "clock gene" transcription-translation feedback loops. Cytosolic Ca2+ mobilization followed by stimulation of various receptors has been shown to reset the gene transcription cycles in SCN neurons, whereas contribution of steady-state cytosolic Ca2+ levels to the rhythm generation is unclear. Recently, circadian rhythms in cytosolic Ca2+ levels have been demonstrated in cultured SCN neurons. The circadian Ca2+ rhythms are driven by the release of Ca2+ from ryanodine-sensitive internal stores and resistant to the blockade of action potentials. These results raise the possibility that gene translation/transcription loops may interact with autonomous Ca2+ oscillations in the production of circadian rhythms in SCN neurons. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Neuroscientist | |||||
書誌情報 |
The neuroscientist : a review journal bridging neurobiology, neurology and psychiatry 巻 10, 号 4, p. 315-324, 発行日 2004-08 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1073-8584 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA1105543X | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 15271259 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1177/10738584031262149 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
出版者 | ||||||
出版者 | Sage | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |