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Prognostic Factors in Elderly Patients with Supratentorial Malignant Gliomas
http://hdl.handle.net/10110/2510
http://hdl.handle.net/10110/2510de650404-ed19-4509-83b9-2fb1fb6143e4
名前 / ファイル | ライセンス | アクション |
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shinkeigeka07-543.pdf (738.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-03-25 | |||||
タイトル | ||||||
タイトル | Prognostic Factors in Elderly Patients with Supratentorial Malignant Gliomas | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | malignant astrocytoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | elderly patient | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | radiation therapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | survival time | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | performance status | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kurimoto, Masanori
× Kurimoto, Masanori× Nagai, Shoichi× Kamiyama, Hironaga× Tsuboi, Yoshifumi× Kurosaki, Kunikazu× Hayashi, Nakamasa× Origasa, Hideki× Endo, Shunro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The prognostic factors were retrospectively analyzed in 30 patients aged 70 years or over with supratentorial malignant gliomas treated by surgery in our hospital. The histological diagnosis was confirmed as grade 3 in 13 patients and grade 4 in 17. Seventeen patients received adjuvant radiation therapy. Only 10 patients underwent chemotherapy. Survival time was analyzed with the Kaplan-Meier method. Prognostic factors were obtained from the Cox proportional hazards model. Univariate analysis showed preoperative Karnofsky performance status (KPS) score of 70 or greater and radiation therapy were significantly associated with longer survival. However, multivariate analysis revealed that preoperative KPS score of 70 or greater was the only independent prognostic factor and radiation therapy lost its significance due to selection bias. Neurological deterioration and medical complications occurred in six and seven patients, respectively. Performance status rather than histological grade is the key prognostic factor in elderly patients with supratentorial malignant gliomas. Patients with good preoperative KPS score should be aggressively treated with extensive resection and radiotherapy. | |||||
書誌情報 |
Neurologia medico-chirurgica : 神経外科 巻 47, 号 12, p. 543-549, 発行日 2007-12 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 4708105 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00358613 | |||||
権利 | ||||||
権利情報 | rights: 本文データは,社団法人 日本脳神経外科学会の許諾に基づき,CiNiiから複製したものである | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 日本脳神経外科学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |