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Effect of Kampo treatment on chronic viral hepatitis on the basis of traditional diagnosis
http://hdl.handle.net/10110/1976
http://hdl.handle.net/10110/19765a1f3ef2-5c94-4200-bc8c-4c796663201c
名前 / ファイル | ライセンス | アクション |
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19990102.pdf (1.2 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-01-25 | |||||
タイトル | ||||||
タイトル | Effect of Kampo treatment on chronic viral hepatitis on the basis of traditional diagnosis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Chronic viral hepatitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hochu-ekki-to(Bu-Zhong-Yi-Qi-Tang) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Prescriptions containing Bupleuri Radix | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Prescriptions corresponding to Ki-deficiency | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Itoh, Takashi
× Itoh, Takashi |
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著者別名 | ||||||
姓名 | 伊藤, 隆 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We investigated the effect of Kampo treatment on 47 patients with chronic viral hepatitis on the basis of traditional diagnosis. The number of patients with hepatitis B and C were 8 and 39, respectively. An improvement in serum alanine aminotransferase (ALT) was observed in 75 % of hepatitis B patients and 44 % of hepatitis C patients after six months of treatment. Symptoms such as easy fatigability and general malaise were improved in 90 % of the patients. Comparing the prognosis of 18 hepatitis C patients treated for more than 3 years with reports on the natural course of the disease following a mean 8.8 years after their first visits, the rate of liver cirrhosis was lower, but the rate of hepatocellular carcinoma and the rate of normalization of liver function were similar. Among the major prescriptions used in this investigation was one that included Bupleuri Radix. Many hepatitis C patients showed a good initial response, but their condition later changed to one indicating prescriptions corresponding to Ki-deficiency. Thus, two kinds of prescriptions could display their effectiveness at different stages of hepatitis C. Following six months of administration of Hochu-ekki-to (補中益気湯; a typical prescription corresponding to Ki-deficiency) to 20 patients with hepatitis C, an improvement of transaminases was observed in the group with a higher Ki-deficiency score, but not in the group with the lower score. These finding were thought to be important for the design of a prospective control study while making the best use of traditional medicine. 慢性B型およぴC型肝炎47症例(B型8例,C型39例)に対する和漢葉随証治療の効果について検討した。治療6ケ月時の血清ALT値の改善はB型75%,C型44%であった。易疲労,倦息感などの症状は両型とも約9割の症例で改善された。治療期間3年以上の18例について平均8.8年の時点で自然経過報告と比較してみると肝硬変への移行率は少なかったが肝細胞痛の発生頻度と臨床的治癒の率は同等であった。使用方剤は両型ともに柴胡剤が多いが,C型の証は柴胡剤で始まり肝障害の進行とともに補剤に変化する傾向を認めた。柴胡剤と補剤には便用すべき時期に相違があるように考えられた。そこで別のC型20例に対して補中益気湯を6ケ月投与したところ,トランスアミナーゼ値は気虚スコア高値群で低下したが,スコア低値群においては変化しなかった。これらの知見を活かしたcontrol studyを企画していく上で重要と考えられた。 |
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書誌情報 |
和漢医薬学雑誌 = Journal of traditional medicines 巻 16, 号 1, p. 7-14, 発行日 1999-04 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13406302 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10486121 | |||||
権利 | ||||||
権利情報 | rights: 本文データは和漢医薬学会の許諾に基づき複製したものである | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 和漢医薬学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |