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The hippocampus plays an important role in eyeblink conditioning with a short trace interval in glutamate receptor subunit delta 2 mutant mice.
http://hdl.handle.net/10110/00018205
http://hdl.handle.net/10110/00018205e6c0bd66-65ba-4b13-9c4c-126a01771993
名前 / ファイル | ライセンス | アクション |
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JNeurosci_23_1_17to22_Kawahara.full (358.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-02-22 | |||||
タイトル | ||||||
タイトル | The hippocampus plays an important role in eyeblink conditioning with a short trace interval in glutamate receptor subunit delta 2 mutant mice. | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | The hippocampus plays an important role in eyeblink conditioning with a short trace interval in glutamate receptor subunit delta 2 mutant mice. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Animals | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Behavior, Animal | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Blinking | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cerebellar Cortex | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Conditioning, Eyelid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hippocampus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Kinetics | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Learning | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Long-Term Synaptic Depression | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mice | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mice, Inbred C57BL | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mice, Knockout | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mutation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Receptors, Glutamate | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Animals | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Behavior, Animal | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Blinking | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cerebellar Cortex | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Conditioning, Eyelid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hippocampus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Kinetics | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Learning | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Long-Term Synaptic Depression | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mice | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mice, Inbred C57BL | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mice, Knockout | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Mutation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Receptors, Glutamate | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takatsuki, Kanako
× Takatsuki, Kanako× Kawahara, Shigenori× Kotani, Sadaharu× Fukunaga, Satoshi× Mori, Hisashi× Mishina, Masayoshi× Kirino, Yutaka |
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その他(別言語等)のタイトル | ||||||
その他のタイトル | The hippocampus plays an important role in eyeblink conditioning with a short trace interval in glutamate receptor subunit delta 2 mutant mice. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Mutant mice lacking the glutamate receptor subunit delta2 exhibit changes in the structure and function of the cerebellar cortex. The most prominent functional feature is a deficiency in the long-term depression (LTD) at parallel fiber-Purkinje cell synapses. These mutant mice exhibit severe impairment during delay eyeblink conditioning but learn normally during trace eyeblink conditioning without the cerebellar LTD, even with a 0 trace interval. We investigated the hippocampal contribution to this cerebellar LTD-independent "0 trace interval" learning. The mutant mice whose dorsal hippocampi were aspirated exhibited severe impairment in learning, whereas those that received post-training hippocampal lesions retained the memory. The wild-type mice showed no impairment in either case. These results suggest that the hippocampal component of the eyeblink conditioning task becomes dominant when cerebellar LTD is impaired. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | The Journal of neuroscience : the official journal of the Society for Neuroscience 23(1), 17-22.(2003) | |||||
書誌情報 |
The Journal of neuroscience : the official journal of the Society for Neuroscience en : The Journal of neuroscience : the official journal of the Society for Neuroscience 巻 23, 号 1, p. 17-22, 発行日 2003-01-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1529-2401 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 12514196 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | the Society for Neuroscience | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |