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According to the diagnostic criteria of \"oketsu\", the \"oketsu\" score (OS) was evaluated. In a sectional study, the results showed that a significant decrease in skin blood flow (SBF) was observed in proportion to the severity of the \"oketsu\" state, and the low-frequency component of SBP (SBP-LF) in the \"oketsu\" state was significantly larger than that in the non-\"oketsu\" state. In a diachronic study, the changes in OS and the parameters between week 0 and 12 weeks later were investigated, with the quantity of each change being calculated as Δ-. Δ-SBF showed a significant negative correlation with Δ-OS, and Δ-RR-L/H, Δ-SBP-LF and Δ-SBP-L/H revealed significant positive correlations with Δ-OS. It is known that SBF changes with sympathetic nervous activity, and SBP-LF and SBP-L/H reflect α-sympathetic nervous activity. 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Correlation between "oketsu" syndrome and autonomic nervous activity
http://hdl.handle.net/10110/1702
http://hdl.handle.net/10110/17021e47d8be-5ba8-41ee-8d27-91c4199fc0c2
名前 / ファイル | ライセンス | アクション |
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wakan04-shibahara.pdf (692.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-01-07 | |||||
タイトル | ||||||
タイトル | Correlation between "oketsu" syndrome and autonomic nervous activity | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | "oketsu" syndrome | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | autonomic nervous activity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | skin blood flow | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | spectral analysis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Shibahara, Naotoshi
× Shibahara, Naotoshi |
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著者別名 | ||||||
姓名 | 柴原, 直利 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In order to clarify the correlation between "oketsu" syndrome and autonomic nervous activity, subjects were evaluated with laser Doppler flowmetry and spectral analyses of R-R intervals (RRs) and systolic blood pressure (SBP). According to the diagnostic criteria of "oketsu", the "oketsu" score (OS) was evaluated. In a sectional study, the results showed that a significant decrease in skin blood flow (SBF) was observed in proportion to the severity of the "oketsu" state, and the low-frequency component of SBP (SBP-LF) in the "oketsu" state was significantly larger than that in the non-"oketsu" state. In a diachronic study, the changes in OS and the parameters between week 0 and 12 weeks later were investigated, with the quantity of each change being calculated as Δ-. Δ-SBF showed a significant negative correlation with Δ-OS, and Δ-RR-L/H, Δ-SBP-LF and Δ-SBP-L/H revealed significant positive correlations with Δ-OS. It is known that SBF changes with sympathetic nervous activity, and SBP-LF and SBP-L/H reflect α-sympathetic nervous activity. These results suggest that α-sympathetic nervous activity increased in the "oketsu" state, and this significant relationship was maintained even after change in the "oketsu" state. 瘀(オ)血病態と自律神経活動との関連性を明らかとするために,レーザードプラ血流計,R-R間隔と収縮期血圧のスペクトル解析を用いて検討した。各対象者について瘀血診断基準により瘀血スコアを算出した。断面的検討では,皮膚血流量(SBF)は瘀血病態の重症化とともに減少し,収縮期血圧低周波数成分(SBP-LF)は軽度及び重度瘀血群が非瘀血群に比較して有意に高値を示した。経時的検討では,SBFの変化量は瘀血スコアと負の相関を示し,R-R間隔成分比(RR-L/H)・収縮期血圧低周波成分(SBP-LF)・収縮期血圧成分比(SBP-L/H)の変化量は瘀血スコアと正の相関を示した。SBFは交感神経活動にともない変化し,SBP-LFはα作動性交感神経活動と関連するとされている。今回の結果は、瘀血病態がα作動性交感神経活動と密接に関連していることを示唆するものである。 |
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書誌情報 |
和漢医薬学雑誌 = Journal of traditional medicines 巻 21, 号 1, p. 1-6, 発行日 2004-02 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18801447 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12035198 | |||||
権利 | ||||||
権利情報 | rights: 本文データは和漢医薬学会の許諾に基づきCiNiiから複製したものである | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 和漢医薬学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |