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Bofutsushosan, a traditional Chinese formulation, inhibits pancreatic lipase activity in vitro and suppresses the elevation of plasma triacylglycerols after oral administration of lipid emulsion
http://hdl.handle.net/10110/1239
http://hdl.handle.net/10110/12399f1a9731-c073-492b-90e4-b0644c31725b
名前 / ファイル | ライセンス | アクション |
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JTrMed22308.pdf (797.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-11-14 | |||||
タイトル | ||||||
タイトル | Bofutsushosan, a traditional Chinese formulation, inhibits pancreatic lipase activity in vitro and suppresses the elevation of plasma triacylglycerols after oral administration of lipid emulsion | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Kampo formulation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pancreatic lipase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | plasma triacylglycerols | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | lipid emulsion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bofutsushosan | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
WATANABE, Shiro
× WATANABE, Shiro× SAITO, Masataka× HAMAZAKI, Tomohito× TANI, Tadato |
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著者別名 | ||||||
姓名 | 渡辺, 志朗 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Pancreatic lipase activity measured as fatty acid liberation from lipid emulsion was shown to be inhibited by the addition of Bofutsushosan (BOF) or Daijokito (DJT) extracts at >30mg/ml. The extracts of Orengedokuto (OGT), Chotosan (CTS), Boiogito (BOT) or Shimbuto (SBT) were ineffective in inhibiting pancreatic lipase activity up to 60mg/ml. Mice were orally administered with a lipid emulsion in the presence of BOF extracts at 750 and 2250mg/kg and subsequent elevation of plasma triacylglycerols (TAG) was significantly suppressed as compared with that in the mice which received lipid emulsion alone. However, the addition of DJT extracts did not suppress the elevation of plasma TAG after oral administration of lipid emulsion. Our results suggest that BOF suppresses the absorption of ingested fats and this effect could account for the anti-obese effects of BOF. | |||||
書誌情報 |
和漢医薬学雑誌 = Journal of traditional medicines 巻 22, 号 6, p. 308-313, 発行日 2005-12 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18801447 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12035198 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
NIIサブジェクト | ||||||
主題Scheme | Other | |||||
主題 | 薬学 | |||||
スポンサー | ||||||
内容記述タイプ | Other | |||||
内容記述 | 21st Century COE program, University of Toyama | |||||
出版者 | ||||||
出版者 | 和漢医薬学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |