A 1-year 8-month-old boy presented with isolated fourth ventricle after ventriculoperitoneal shunting for hydrocephalus assotiated with ventricular and subarachnoid hemorrhage.The therapeutic endoscope was inserted through the thin left cerebellar hemisphere.Endoscopic aqueductal plasty was performed via the enlarged fourth ventricle under guidance from a navigating system.Endoscopic aqueductal plasty via the fourth ventricle under navigating system guidance is a useful procedure enabling less invasive surgery for isolated fourth ventricle associated with slit-like ventricle after shunt placement.