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Effect of a Platelet-Activating Factor Receptor Antagonist, E5880, on Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage : Open Clinical Trial to Investigate Efficacy and Safety
http://hdl.handle.net/10110/2035
http://hdl.handle.net/10110/203545c1f0dd-d4f8-4e87-9a99-b1ac99b70ce7
名前 / ファイル | ライセンス | アクション |
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shinkeigeka01-165.pdf (1.3 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-01-30 | |||||
タイトル | ||||||
タイトル | Effect of a Platelet-Activating Factor Receptor Antagonist, E5880, on Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage : Open Clinical Trial to Investigate Efficacy and Safety | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cerebral vasospasm | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | subarachnoid hemorrhage | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | platelet-activating factor receptor antagonist | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Hirashima, Yutaka
× Hirashima, Yutaka× Endo, Shunro× Nukui, Hideaki× Kobayshi, Naoki× Takaku, Akira |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The efficacy and safety of a new platelet-activating factor receptor antagonist, E5880, were investigated for preventing cerebral vasospasm after subarachnoid hemorrhage (SAH) in 71 patients with SAH who underwent surgery for ruptured aneurysms within 3 days. Intravenous E5880 administration (300 μg or 1200 μg twice daily) was begun within 4 days and continued for 14 days. The incidence of symptomatic vasospasm, low-density area on computed tomography, and angiographic vasospasm was lower than in placebo groups in previous studies. Clinical outcome was favorable compared with previous studies. No clinically important adverse events were observed. These results suggest that E5880 is safe and effective in the treatment of patients with cerebral vasospasm due to SAH. | |||||
書誌情報 |
Neurologia medico-chirurgica : 神経外科 巻 41, 号 4, p. 165-176, 発行日 2001-04 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 4708105 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00358613 | |||||
権利 | ||||||
権利情報 | rights: 本文データは日本脳神経外科学会の許諾に基づきCiNiiから複製したものである | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 日本脳神経外科学会 | |||||
資源タイプ(DSpace) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |